Protein that Makes the Difference Between Healthy and Unhealthy Obesity Discovered
Angpt2 produced from fat cells interacts with its receptor integrin α5β1 to drive fatty acid transporters (CD36 and FATP3) and ensures normal circulating fat. If this Angpt2–integrin α5β1 signaling does not work, defects in buffering capacity of fat tissue lead to fat spillover into the liver and muscle, convert brown fat to white fat, and consequently result in defects in metabolic health.
(Picture: IBS)
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![Dr. E. Poonguzhali has successfully transferred commercially available starting materials to medicinally important 2-acylbenzo[b]thiophenes in the presence of copper acetate & tetrabutylammonium chloride catalytic system.](https://cdn1.vogel.de/ZK7wqjVy7Ps1OSwUs5tXgrNZGEE=/288x162/smart/filters:format(jpg):quality(80)/images.vogel.de/vogelonline/bdb/1964500/1964559/original.jpg "Dr. E. Poonguzhali has successfully transferred commercially available starting materials to medicinally important 2-acylbenzo[b]thiophenes in the presence of copper acetate & tetrabutylammonium chloride catalytic system.")
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/cdn4.vogel.de/infinity/white.jpg "Angpt2 produced from fat cells interacts with its receptor integrin α5β1 to drive fatty acid transporters (CD36 and FATP3) and ensures normal circulating fat. If this Angpt2–integrin α5β1 signaling does not work, defects in buffering capacity of fat tissue lead to fat spillover into the liver and muscle, convert brown fat to white fat, and consequently result in defects in metabolic health.")
