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Mass Spectrometry Improved Ease and Reliability of Small Molecule Analysis

Editor: Alexander Stark

The new Acquity RDa Detector by Waters facilitates the acquisition of high-quality, accurate-mass data for routine small molecule applications. Its Smart MS technology helps speed decision-making and delivers consistent, reproducible results.

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Waters Corporation
The Acquity RDa Detector featuring SmartMS technology is a time-of-flight mass detector for making accurate-mass measurements of small molecules during pharmaceutical impurity analyses, forced degradation studies, food and natural products analyses and seized drug profiling.
The Acquity RDa Detector featuring SmartMS technology is a time-of-flight mass detector for making accurate-mass measurements of small molecules during pharmaceutical impurity analyses, forced degradation studies, food and natural products analyses and seized drug profiling.
(Source: Waters)

Waters Corporation released the Acquity RDa Detector featuring Smart MS, the company’s newest time-of-flight (TOF) mass spectrometer (MS) for small molecule analysis for pharmaceutical, academic, food, and forensics applications. The accurate-mass detector can be quickly deployed and operated to enable faster and more informed decision-making across a broad set of applications, the company states.

From setup to results, the detector is designed for ease-of-use with intuitive system health checks and dedicated results-oriented workflows. With Smart MS, users can identify analytes more accurately and confidently evaluate outcomes with end-to-end robust, reliable workflows for routine applications. Paired with a simple one-button start, the RDa Detector reduces the extent of training, limits downtime, and ensures consistent, reproducible results.

The ACQUITY RDa Detector is optimized for small molecule applications where quality, compliance and data integrity are critical. These include impurity analysis, forced degradation studies, lipid screening, natural products profiling, food contaminant analysis, seized and controlled drug profiling, and general accurate-mass measurements.

For improved usability and faster outcomes, the detector operates on Waters Connect, an open software platform designed to enhance the value that the RDa brings to laboratories with new functionality, features and software updates. Providing a complete audit trail for acquisition, processing and reporting of data, the software platform enables seamless compliance and the highest standards of data integrity. With the option of system qualification, the platform is suitable for regulated and non-regulated laboratories alike.

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