Flow Monitoring System Improves Direct Comparison, Transferability of HPLC Methods

Real-time Solutions Flow Monitoring System Improves Direct Comparison, Transferability of HPLC Methods

2026-05-31 Source: Press release Testa Analytical 1 min Reading Time

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Testa Analytical’s Flowchrom real-time flow monitoring system boasts of enhancing direct comparison and transferability of HPLC methods and results between instruments in different locations.

Equipping all your HPLC systems running standard separation protocols with an automated non-invasive flow monitoring system, such as Flowchrom, is the only true solution. (Source: Testa Analytical) — Equipping all your HPLC systems running standard separation protocols with an automated non-invasive flow monitoring system, such as Flowchrom, is the only true solution.
(Source: Testa Analytical)

It is not uncommon for organizations to have multiple HPLC systems performing the same separation protocol in several labs across larger sites or distributed worldwide. Particularly in industries such as pharma, food and agriculture - labs must comply with regulated laboratory data quality standards set by guidelines like Good Laboratory Practices (GLP) and international standards such as ISO/IEC 17025, mentions the company.

The challenge for corporations is to ensure that methods, and therefore results obtained, are comparable across sites. Transferability of analytical methods is therefore a must. One strategy is to equip all labs with the same HPLC/UHPLC systems, assuming this will help achieve the said goal, adds the firm. Experience has shown though that even identical HPLC systems, running standard separation protocols, tend to deliver slightly different results, often inexplicably.

Equipping all your HPLC systems running standard separation protocols with an automated non-invasive flow monitoring system, such as Flowchrom, is the only true solution, shares the firm. Using measured flow data instead of assuming the set flow is reproduced identically by each instrument, is the only safe tool to reveal hidden differences in operation of even identical HPLC systems. This elegant and affordable real-time flow monitoring solution has been proven to allow analytical labs to pinpoint and correct flaws and thereby achieve robust lab to lab interoperability and transferability of HPLC methods and results, opines the company.

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