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Fig.1: There are several therapeutic Antibodies currently in late stages of clinical trials (representative picture). (©psdesign1 - stock.adobe.com)
Size Exclusion Chromatography and UHPLC

Chromatography: Size Matters

Quick and straightforward, aqueous size exclusion chromatography (SEC) has become a mainstay for the analysis of protein aggregates in the biopharmaceutical industry. Coupling SEC with advanced detection, such as mass spectrometry, light scattering or surface plasmon resonance, makes it a versatile tool for numerous applications beyond aggregate analysis.

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