Researchers have developed a low-cost and easy to produce wood tongue depressor that has the capability to check the levels of glucose and other biomarkers in the saliva. In the future, this solution may also help doctors to examine numerous health conditions.
Electrochemical cells etched by a laser on a wooden tongue depressor can measure glucose and nitrite levels in saliva. (WE = working electrode, CE = common counter electrode, RE = common reference electrode)
(Source: Adapted from Analytical Chemistry, 2023, DOI: 10.1021/acs.analchem.3c01211)
Washington/USA – Doctors often use tongue depressors when peering in a patient’s mouth and throat. But what if that flat wooden spatula could actively evaluate the patient’s health? That’s the premise of an ecofriendly disposable sensor, reported in ACS’ Analytical Chemistry, that can check levels of glucose and other biomarkers in saliva. Researchers say the easy-to-produce device could someday help doctors assess a range of conditions.
Wood is a renewable, biodegradable, natural material that is widely available at low cost, which makes it attractive for researchers who design electronics and sensors. However, this is challenging because the material isn’t good at conducting electricity. One solution is to use wood as a passive substrate and then coat it with metals and carbon-based inks. Alternatively, high-power lasers can char specific regions on the wood, turning those spots into conductive graphite. But this complicated technique requires sophisticated and expensive instrumentation, an oxygen-free atmosphere and fire retardants. To develop a cheaper and easier process, Christos Kokkinos and colleagues turned to low-power diode lasers, which have already been successfully used to make polyimide-based sensors but haven’t previously been applied to wooden electronics and electrochemical sensors.
The team used a portable, low-cost laser engraver to create a pattern of conductive graphite electrodes on a wooden tongue depressor, without the need for special conditions. Those electrodes formed two electrochemical cells separated by lines drawn with a water-repellent permanent marker. The biosensor was then used to rapidly and simultaneously measure concentrations of nitrite and glucose in artificial saliva. Nitrite can reveal oral diseases, such as periodontitis, while glucose can serve as a diagnostic for diabetes. The researchers say these low-cost devices could be adapted to detect other saliva biomarkers and would be quick and easy to produce on-site at medical facilities.
The researchers did not receive outside funding for the study.
(ID:49422664)
Stand vom 23.03.2021
Naturally, we always handle your personal data responsibly. Any personal data we receive from you is processed in accordance with applicable data protection legislation. For detailed information please see our privacy policy.
Consent to the use of data for promotional purposes
I hereby consent to Vogel Communications Group GmbH & Co. KG, Max-Planckstr. 7-9, 97082 Würzburg including any affiliated companies according to §§ 15 et seq. AktG (hereafter: Vogel Communications Group) using my e-mail address to send editorial newsletters. A list of all affiliated companies can be found here
Newsletter content may include all products and services of any companies mentioned above, including for example specialist journals and books, events and fairs as well as event-related products and services, print and digital media offers and services such as additional (editorial) newsletters, raffles, lead campaigns, market research both online and offline, specialist webportals and e-learning offers. In case my personal telephone number has also been collected, it may be used for offers of aforementioned products, for services of the companies mentioned above, and market research purposes.
In case I access protected data on Internet portals of Vogel Communications Group including any affiliated companies according to §§ 15 et seq. AktG, I need to provide further data in order to register for the access to such content. In return for this free access to editorial content, my data may be used in accordance with this consent for the purposes stated here.
Right of revocation
I understand that I can revoke my consent at will. My revocation does not change the lawfulness of data processing that was conducted based on my consent leading up to my revocation. One option to declare my revocation is to use the contact form found at https://support.vogel.de. In case I no longer wish to receive certain newsletters, I have subscribed to, I can also click on the unsubscribe link included at the end of a newsletter. Further information regarding my right of revocation and the implementation of it as well as the consequences of my revocation can be found in the data protection declaration, section editorial newsletter.