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A discovery by Scripps Research scientists may offer insight into treating blood disorders such as sickle cell anemia. (The Scripps Research Institute)
USA: Sickle Cell Diseases

How Blood Cells Keep Their Shape

In a new study, Velia Fowler, PhD, and her lab at The Scripps Research Institute report that a protein called myosin IIA contracts to give red blood cells their distinctive shape. The findings, published this week in the journal Proceedings of the National Academy of Sciences, could shed light on sickle cell diseases and other disorders where red blood cells are deformed.

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Serendipity: Professor John McGeehan and colleagues inadvertently engineered an enzyme better at degrading plastic than the enzyme which evolved in nature. (Stefan Venter)
UK: Degradation of Plastic

UK Scientists Engineer Plastic-Eating Enzyme

Scientists at the University of Portsmouth have engineered an enzyme which can digest some of our most commonly polluting plastics. The discovery could result in a recycling solution for millions of tonnes of plastic bottles, made of polyethylene terephthalate, or PET, which currently persists for hundreds of years in the environment.

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Sanofi’s acquisition of Principia Biopharma will allow expansion of the SAR442168 development programme into other central nervous system diseases and therapeutic areas.  (Deposit Photos )
Business Deal

Sanofi to Takeover Principia Biopharma

With this acquisition, Sanofi aims to further strengthen its core R&D areas of autoimmune and allergic diseases. The move will also provide full control of the brain-penetrant BTK inhibitor SAR442168 in multiple sclerosis which is expected to make commercialisation more efficient and eliminate royalty payments in the future.

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A male stickleback (Gasterosteus aculeatus) during spawning time. (Joakim Hansen/Azote)
Sweden: Ecology

A Wave of Sticklebacks: How a Tiny Fish Takes Over an Entire Ecosystem

Large numbers of three-spined stickleback have gradually taken over larger parts of the Baltic Sea’s coastal ecosystem, shows a new scientific study. Stickleback is a small prey fish common in aquatic food webs across temperate Europe. The stickleback contributes to local ecosystem ‘regime shifts’, where young-of-the-year pike and perch decline in individual bays, and these shifts gradually spread like a wave from the outer archipelago into the mainland coast.

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