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Artistic depiction of human mitochondrial ribonuclease P. A rendering of the three-dimensional model of mtRNase P is depicted in the foreground with protein subunits in grey and RNA in red, and the typical cristae-structure of mitochondrial membranes and associated protein complexes are depicted in the background. (Arjun Bhatta / Max Planck Institute for Biophysical Chemistry)
Germany: Molecular Biology

First High-Resolution Glimpse of the Powerhouse of Human Cells

Scientists at the Max Planck Institute (MPI) for Biophysical Chemistry and the University Medical Center Göttingen (UMG) have determined the molecular mechanism of the first step of RNA processing in human mitochondria. This step is carried out by an enzyme complex called mitochondrial ribonuclease P (mtRNase P). The scientists visualized the structure of this molecular RNA cutting machine using cryo-electron microscopy (cryo-EM). This reveals for the first time how mitochondrial RNAs are cut, and explains why mutations in the involved proteins lead to disease in humans.

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Tension in the air: when they are nervous, cinema-goers release more isoprene, which is a measurable indication of how stressful a film is. (Jonathan Williams, MPI for Chemistry)
Ig Nobel Prize in Chemistry

Innovative Movie Rating: Air Measurement in the Cinema

The Ig Nobel Prizes honour scientific achievements that “should first make people laugh and then make them think”. The spoof prizes, first awarded by the US journal Annals of Improbable Research in 1991, have long since acquired cult status among scientists. This year’s chemistry award recognizes a study that proves the connection between the air in cinemas and different age ratings. The study was carried out in cooperation between the Max Planck Institute for Chemistry and the University of Mainz.

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