The Orion project is part of the flagship initiative, ‘Artificial Intelligence in the Life Sciences, from a Human Health Perspective’ by Swiss Federal Innovation Agency Innosuisse. The goal of the research project is to help improve the treatment of each cancer patient.

In a promising advance for cancer treatment, Northwestern University scientists have re-engineered the molecular structure of a common chemotherapy drug, making it dramatically more soluble and effective and less toxic.

The types of fats we consume directly impacts the survival and strength of the body’s immune cells and ability to fight disease, researchers have found.

Researchers have developed an AI-based platform that can map disease-related changes across the entire mouse body at cellular resolution. Using Mouse Mapper, the team identified widespread inflammation and previously unknown obesity-related damage to facial sensory nerves, and it found corresponding molecular signatures in human tissue.

The precise pH monitoring is crucial for the stability and performance of nanoparticles in drug delivery. Read how these biocompatible materials are developed and at what step the pH measurement is incorporated into the process.

Researchers have developed a mechanophenotyping cytometer — a microfluidic device designed to measure a cell’s physical size and squishiness. With the help of this new device, accurate measurements of changes in cell elasticity can be used to better understand diseases, diagnose patient symptoms and provide more accurate prognoses.

How much people drink matters — but so does what they drink. A new large-scale study suggests that low to moderate wine consumption may be associated with lower cardiovascular risk, while even modest intake of beer, cider or spirits was linked to higher mortality.

A new AI model developed at Stanford can analyse data from a single night’s sleep to predict the risk of more than 100 diseases — years before symptoms appear — opening a new window on preventive and precision medicine.

Ultra-processed foods may pose health risks not only because of their nutrient profile, but also because of how they are made. A Tufts University study suggests that industrial processing, additives and changes to food structure could help explain links with diabetes, heart disease and early death, even when overall diet quality is taken into account.

Targeted brain stimulation with low-intensity ultrasound could open a new non-invasive route for chronic pain treatment. Researchers found that transcranial ultrasound stimulation of a brain region involved in pain processing did not immediately reduce pain intensity, but appeared to alter pain perception and brain connectivity in the following hour.