Researchers see promise in a class of natural antimicrobials called microcins, which are produced by bacteria in the gut and help them compete with rival bacteria. The researchers also identify the first known microcin that targets the strains of bacteria that cause cholera and describe a method for finding microcins in bacterial genomes with the help of artificial intelligence.

Human breast milk regulates a baby’s mix of microbes, or microbiome, during the infant’s first year of life. This in turn lowers the child’s risk of developing asthma, a new study shows.

Researchers at the University of Sheffield have discovered how a hospital superbug Clostridioides difficile (C.diff) can rapidly evolve resistance to vancomycin, the frontline drug used in the UK. The scientists found that in less than two months the bacteria could develop resistance to 32 times the initial antibiotic concentration.

Researchers at Umeå University, Sweden, have discovered how the enzyme PrgK helps spread antibiotic resistance among bacteria by breaking down their cell walls. This enzyme, part of the type 4 secretion system (T4SS), allows resistance genes to transfer between bacteria. Understanding the role of PrgK and its domains is a key step towards preventing the spread of antibiotic resistance.

Pet dogs and cats play an important role in the spread of antibiotic-resistant bacteria, new research presented at the Escmid Global Congress in Barcelona, Spain (27-30 April) suggests.

In a new study, researchers have discovered a potential new avenue to treat or prevent cholera. They have identified a unique quirk of the immune system that protects the cholera bacteria from a key driver of bacterial evolution.

Stanford Medicine introduces Synthemol, an AI model crafting new drugs against superbugs. Amid a global crisis with nearly five million deaths yearly from antibiotic resistance, this tool offers hope by designing and synthesizing six promising compounds in record time.

UC Davis researchers have uncovered how changes in the gut microbiome can lead to sorbitol intolerance, revealing a connection between antibiotic use, diet, and digestive health.

Researchers have successfully modified DNA from four types of phages to kill a deadly pathogen. The process can also be used to produce more phage variants for further exploration.

Researchers have analysed the rise of antibiotic resistance over the last 20 years in the UK and Norway, highlighting that antibiotic use is not the only factor in the increase.