Gene editing could help solve one of the biggest problems in treating aggressive blood cancers: how to attack cancer cells without destroying healthy donor cells. A new multicentre trial shows that CRISPR-modified stem cell transplants may make CD33-targeted therapies safer and more effective after transplantation.

Nearly half of dementia cases could be prevented by tackling modifiable risk factors such as physical inactivity, smoking, low education or social isolation, but new Curtin University research suggests current public health approaches are falling short of driving real behaviour change.

Researchers have developed a new laboratory model to study rare tumors—BAP1-deficient melanomas—that are resistant to immunotherapies. The model has the potential to transform how therapies are developed for aggressive melanomas that currently have almost no effective treatment options.

Regular exercise can significantly reduce symptoms of depression and anxiety — in many cases as effectively as medication or psychotherapy.

The determination of volatile organic compounds (VOCs) in postharvest analysis using gas chromatography coupled with mass spectrometry (GC–MS) has proven to be a suitable tool for predicting the extent of chilling injury and minimizing food losses. The peach example presented here may serve as a model case for other commodities.

A gene shared by salamanders, zebrafish and mice could point toward a new path for regenerative medicine: researchers have identified key genetic programs involved in regrowth and used them to partially restore digit regeneration in mice. The findings do not bring human limb regeneration within immediate reach, but they offer a promising proof of principle for future gene-based therapies.

In a new study, scientists have found that residential wood burning is a major contributor to winter air pollution across the United States. It further states that although only 2 % of U.S. homes rely on wood as their primary heating source, residential wood burning accounts for more than one-fifth of Americans’ wintertime exposure to outdoor fine particulate matter (PM2.5).

New research from Virginia Tech identifies key molecular changes behind age-related memory loss — and shows they can be reversed. By targeting specific brain processes with advanced gene-editing tools, scientists improved memory performance in older animals, opening new possibilities for dementia research.

Researchers have found that parents think that their children are getting sufficient sleep but that not the case as a study in Rhode Island in the USA reveals that kids sleep less than their parents realize.

New research highlights that food anaphylaxis, a severe and rapid allergic reaction to food, can prove fatal in children if life-saving adrenaline autoinjector (Epipen) is not administered on time.