Gene editing could help solve one of the biggest problems in treating aggressive blood cancers: how to attack cancer cells without destroying healthy donor cells. A new multicentre trial shows that CRISPR-modified stem cell transplants may make CD33-targeted therapies safer and more effective after transplantation.

Researchers have developed a new laboratory model to study rare tumors—BAP1-deficient melanomas—that are resistant to immunotherapies. The model has the potential to transform how therapies are developed for aggressive melanomas that currently have almost no effective treatment options.

A gene shared by salamanders, zebrafish and mice could point toward a new path for regenerative medicine: researchers have identified key genetic programs involved in regrowth and used them to partially restore digit regeneration in mice. The findings do not bring human limb regeneration within immediate reach, but they offer a promising proof of principle for future gene-based therapies.

New research from Virginia Tech identifies key molecular changes behind age-related memory loss — and shows they can be reversed. By targeting specific brain processes with advanced gene-editing tools, scientists improved memory performance in older animals, opening new possibilities for dementia research.

Researchers have recently tested a Crispr/Cas9 gene-editing technique to help the immune system in a person’s body to fight advanced gastrointestinal cancers. The results have revealed promising signs of safety and potential effectiveness of the treatment.

Researchers at Kaist have developed the first technology to selectively acetylate specific RNA molecules inside living cells using the CRISPR-Cas13 system. This breakthrough enables precise, programmable control of RNA function and marks a major step forward in RNA-based therapeutics and gene regulation research.

Researchers at the University of Pennsylvania have discovered a way to make mRNA vaccines safer and more effective — by adding anti-inflammatory molecules inspired by olive oil. Their new lipid design not only reduces side effects like soreness and fatigue but also boosts vaccine performance against diseases like Covid-19 and cancer.

The platform called Nanostraw Electro-actuated Transfection (Next) uses tiny hollow nanostructures and electrical pulses to insert a wide variety of biomolecules — proteins, mRNA and gene-editing tools — into immune cells with high efficiency and minimal disruption.

A breakthrough enzyme discovered in Brazil could transform biofuel production. Named Celoce, the natural protein efficiently breaks down cellulose — one of biomass's toughest components — offering a powerful new tool for producing second-generation ethanol from agricultural waste.

Chemists at Oak Ridge National Laboratory have developed a groundbreaking method to upcycle discarded plastics into superior materials with enhanced properties. By editing polymer structures at the molecular level, this innovative approach could revolutionize recycling, reduce waste, and pave the way for a sustainable circular economy.