German China
Whole-body 3D reconstruction
 (Source: Ali Ertürk Lab/ Helmholtz Munich)
Mouse Mapper

AI Platform Reveals Hidden Nerve Damage Linked to Obesity

Researchers have developed an AI-based platform that can map disease-related changes across the entire mouse body at cellular resolution. Using Mouse Mapper, the team identified widespread inflammation and previously unknown obesity-related damage to facial sensory nerves, and it found corresponding molecular signatures in human tissue.

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Big dogs tend to age faster than small dogs. Now, we know why. A new study led by researchers at Arizona State University offers the first compelling molecular explanation of why large dogs live shorter lives: the answer may lie in how hallmarks of aging reshape dog DNA. 
 (Source: Charlie Leight, Arizona State University)
Understanding Aging

Why Big Dogs Age Faster

Why do large dogs tend to live shorter lives? A study of 864 dogs links body size to faster loss of DNA methylation at regions containing “jumping genes”. The findings offer a possible molecular explanation for differences in canine ageing, although whether these changes help drive ageing remains unclear.

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