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Scientists from Gladstone and UCSF have shed light on exactly how neurons consume and metabolize glucose, which could have implications for understanding neurodegenerative diseases. Seen here are Ken Nakamura (left), Yoshi Sei (center), and Myriam Chaumeil (right). (Source: Michael Short/Gladstone Institutes)
Glucose Metabolization

Sugar Rush: Key Role of Glucose in Brain Activity Discovered

The human brain has a sweet tooth, burning through nearly one quarter of the body’s sugar energy, or glucose, each day. Now, researchers at Gladstone Institutes and UC San Francisco (UCSF) have shed new light on exactly how neurons — the cells that send electrical signals through the brain — consume and metabolize glucose, as well as how these cells adapt to glucose shortages

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Shah’s team engineered living tumor cells using the gene editing tool Crispr-Cas9 and repurposed them to release tumor cell killing agent.  (Source: Pixabay)
Cell Therapy

Testing the Cancer Vaccine

Scientists at the Brigham and Women’s Hospital have tested a new cancer vaccine which kills as well as prevents brain cancer. The experts used a new cell therapy approach to eliminate established tumors and train the immune system to prevent cancer from recurring in the future.

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It is a long way from motorization to true automation in imaging. (Zeiss)
Microscopy & Automation

Long Way from Motorization to True Automation

Rapid developments at all levels of microscopy, such as contrast, illumination, resolution, signal detection and data processing have occurred over the last decades and there is reason to expect that these advances will continue. However, severe limitations in accuracy, reproducibility and throughput are caused by the involvement of humans in all steps of the imaging workflow. It also poses a significant burden and workload for the researcher. To improve this situation is the biggest challenge in automation.

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