A study from Cold Spring Harbor Laboratory highlights a new target in Alzheimer’s research: blocking the enzyme PTP1B restored learning and memory in mice by reactivating the brain’s own immune cells to clear amyloid plaques. The results open the door to combination therapies that could go beyond current plaque-focused treatments and slow disease progression.

Long-term exposure to fine particulate air pollution is associated with a higher risk of Alzheimer’s disease, according to a large national study of nearly 28 million older adults in the United States.

A study has revealed that a simple three-minute brainwave test can help to identify memory problems in people with Mild Cognitive Impairment, a condition that can lead to Alzheimer’s disease.

A new study has found that as super agers (a unique group of adults over age 80 whose performance on tests of episodic memory was equal to or better than that of people in their 50s) age their brain continues to generate new neurons in the hippocampus at much higher levels than older adults and even younger individuals.

A simple blood test could help identify women at increased risk of dementia up to 25 years before symptoms appear. In a long-term study, higher levels of the biomarker p-tau217 were strongly linked to later cognitive decline, highlighting the potential of blood-based testing for earlier risk assessment and prevention research.

Altering the gut microbiome could help the brain recover after traumatic injury. Researchers at Houston Methodist report in Communications Biology that short-term antibiotic treatment reduced neuroinflammation and tissue damage in experimental models of traumatic brain injury.

A widely anticipated clinical trial has delivered disappointing results: the antiviral drug valacyclovir, commonly used to treat herpes infections, showed no benefit in slowing early-stage Alzheimer’s.

A large long-term study from Sweden links higher consumption of high-fat cheese and cream to a lower risk of dementia — challenging long-standing assumptions about dietary fat and brain health, while underscoring the need for further research.

A new study has revealed that signs of the Alzheimer’s disease could be detected as early as middle age and that blood-based biomarkers associated with Alzheimer's disease can be used in the future to detect the disease early on.

New research from Virginia Tech identifies key molecular changes behind age-related memory loss — and shows they can be reversed. By targeting specific brain processes with advanced gene-editing tools, scientists improved memory performance in older animals, opening new possibilities for dementia research.