Despite substantial investment in pharmaceutical R&D, clinical success rates remain low. As it stands, 90 % of drug candidates entering human trials fail due to unforeseen toxicity or limited efficacy in humans. A key contributor to this attrition is the limited predictive power of traditional preclinical models, particularly 2D cell cultures and animal studies, which often fall short in recapitulating the complexity of human biology. This gap is particularly evident in oncology and organ-specific toxicity assessments, where cellular context and microenvironmental interactions play a critical role in drug response.

Honey bees navigate with striking individual precision, according to a drone-based study by researchers at the University of Freiburg. High-resolution 3D tracking shows that each bee follows its own consistent route between hive and food source, using landscape landmarks to stay on course. The findings reveal far greater navigational accuracy than previously assumed from the waggle dance.

A new study has revealed that a father’s diet before conception has the potential to influence placenta development and fetus growth. The study focused on male mice that were fed different diets for eight weeks before mating.

The EU’s carbon border adjustment could do more than protect European industry from carbon leakage. A new PIK-led study suggests that CBAM may also push major trading partners such as Canada, Japan, South Korea and Taiwan to adopt their own carbon pricing, significantly increasing global emissions reductions.

Researchers in Germany have uncovered how elephants achieve their remarkable tactile precision: the whiskers covering their trunks combine a stiff base with a soft, resilient tip, creating a built-in sensing gradient.

Soft, stretchable and adhesive bioelectronics could bring wearable and implantable biosensors closer to long-term medical use. New Caltech studies show how flexible materials, wet-tissue adhesion and closed-loop sensing platforms may enable continuous monitoring and adaptive therapy inside and outside the body.

A new robotic hand makes use of the Forte technology to grasp objectives that are sensitive to touch such as a potato chip or raspberries without crushing it. The innovation has the potential to improve robot performances in food processing, health care and manufacturing.

Scientists have developed a new technology that can eavesdrop on the hidden electrical dialogues unfolding inside ‘mini brains’ also called as human neural organoids.

Researchers in Austria have shown that swimming E. coli can generate enough hydrodynamic torque in confined spaces to rotate tiny symmetric discs. The finding sheds new light on how bacteria behave in tight environments and could help inspire new soft materials and microscopic contactless engines.

A University of Nottingham study shows plant-based dog foods dramatically reduce land use, emissions, and resource demand compared to red-meat diets — offering pet owners a way to shrink their dog’s environmental “paw-print” without sacrificing nutrition.