Sample Protection More Efficient Closed-System Handling of Critical Sterile Liquids
Editor: Alexander Stark
Bioprocess researchers undertaking high-density mammalian, bacterial or microbial cell culture separations can now benefit from a next-generation single-use, sterilized, closed-system Bioprocess Container (BPC) from Thermo Fisher Scientific designed to offer a highly efficient alternative for harvesting by centrifugation.
The Thermo Scientific Centripak BPC in the Thermo Scientific Sorvall Bios 16 Centrifuge.
(Source: Thermo Fisher Scientific)
Waltham/USA — Developed specifically for use with the Thermo Scientific Sorvall Bios 16 Centrifuge, the single-use, sterilized, closed-system Thermo Scientific Centripak BPC enables optimal protection of critical sterile liquids from cross-contamination typically associated with reusable containers. The Centripak BPC can be used to process culture volumes of between 3 and 500 l, facilitating high-throughput and high-efficiency cell biomass or clarified supernatant harvesting to maximize laboratory productivity. Furthermore, there are no time-consuming, labor-intensive and costly preparation and post-use cleaning steps involved.
To ensure it meets the high-quality standards expected in the bioprocessing industry, the Centripak BPC is subject to thorough quality control procedures, in compliance with cGMP and ISO 13485:2016. Thermo Fisher’s rigorous production control process provides complete lot traceability for each batch, with relevant documentation accompanying the lot through every step of the manufacturing cycle. At the end of the process, the Certificate of Analysis provided with the Centripak BPC reports compliance of all product contact materials and films to USP<88>, USP<87>, USP<661>, EP<3.2.2.1> and EMEA/410/01. Routine testing is performed on representative samples in periodic validations for USP<85>, USP<788> and ANSI/AAMI/ISO 11137. The BPC is available in various configurations, and comes with a full suite of accessories, including adapters, racks, clips, and spacers.
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