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The Empa skin model: gelatine on a cotton substrate (Empa)
Switzerland: Material Research

Gelatine Skin Model Replaces Experiments on Humans

The characteristics of human skin are heavily dependent on the hydration of the tissue. Its water content also changes its interaction with textiles. Up to now, it has only been possible to determine the interaction between human skin and textiles by means of clinical trials on human subjects. Now, Empa researchers have developed an artificial gelatine-based skin model that simulates human skin.

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A chronic bacterial infection, a flame retardant, and six water disinfection byproducts are listed in a new HHS cancer report. (Public Domain)
USA: Report on Carcinogens

Eight Additional Substances Classified as Carcinogenic

Eight substances have been added to the US Report on Carcinogens, bringing the total list to 256 substances that are known, or reasonably anticipated, to cause cancer in humans. This is the 15th Report on Carcinogens, which is a cumulative report, mandated by Congress and prepared by the National Toxicology Program (NTP) for the Secretary of the U.S. Department of Health and Human Services.

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IUPAC has put together the 10 most promising innovations in chemistry for a more sustainable world (symbol image). (creative commons, markmags)
Chemical Developments of the Future

The 10 Chemical Innovations with the Highest Sustainability Potential

Since the establishment of the Periodic Table of Elements (PSE) 150 years ago, not only the number of known elements has increased, but new technologies have also emerged: Chemical pesticides to protect the harvest, batteries for energy on the move and plastics in every form, color, and function. The current focus is on the sustainability aspect. But here, too, chemistry offers new solutions. The 10 most promising technologies for a more sustainable world have been selected by the chemical association IUPAC.

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Lp-PLA2 in its “closed” conformation (left) and “open” conformation (right) once bound to the phospholipid monolayer. (UC San Diego Health Sciences)
USA: Computer Simulation

Movie Starring an Enzyme May Lead to New Drugs for Cardiovascular Disease

Membrane-associated proteins play a vital role in a variety of cellular processes, yet little is known about the membrane-association mechanism. Lipoprotein-associated phospholipase A2 (Lp-PLA2) is one such protein with an important role in cardiovascular health, but its mechanism of action on the phospholipid membrane was unknown. To address this, researchers used experimental and computational tools.

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