German China
An up-close look at a mouse’s liver; the cells with dark centers were turned cancerous using a new gene-editing strategy devised by Semir Beyaz’s lab. (Source: Beyaz lab/Cold Spring Harbor Laboratory)
Cancer Research

CRISPR Reveals Multiple Personalities of Cancer Cells

Mutations in our genes can lead to severe problems, like colon or liver cancer. But cancer is very complex. Mutations in the same genes can lead to different subtypes of tumors in different people. Currently, there is no good way to produce such tumor subtypes for study. Now, scientists created a method to model certain liver cancer tumor subtypes using the gene-editing tool CRISPR-Cas9.

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