Nanoparticles from the Energy Sector to Treat Sepsis
A tailored amount of zirconium ions (Zr4+) in the 7CZ nanoparticles (7CZ NP) boost their performance as antioxidants: they are more efficient in converting Ce4+ into Ce3+ compared with the traditional ceria nanoparticles (Ceria NP), therefore a smaller dose suffice. After sepsis was induced in rats and mice with a puncture in the cecum (CLP), injection of 7CZ nanoparticles resulted in an increase in survival rate and a decrease in organ injuries.
(Picture: Institute for Basic Science )
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![Dr. E. Poonguzhali has successfully transferred commercially available starting materials to medicinally important 2-acylbenzo[b]thiophenes in the presence of copper acetate & tetrabutylammonium chloride catalytic system.](https://cdn1.vogel.de/ZK7wqjVy7Ps1OSwUs5tXgrNZGEE=/288x162/smart/filters:format(jpg):quality(80)/images.vogel.de/vogelonline/bdb/1964500/1964559/original.jpg "Dr. E. Poonguzhali has successfully transferred commercially available starting materials to medicinally important 2-acylbenzo[b]thiophenes in the presence of copper acetate & tetrabutylammonium chloride catalytic system.")
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/cdn4.vogel.de/infinity/white.jpg "A tailored amount of zirconium ions (Zr4+) in the 7CZ nanoparticles (7CZ NP) boost their performance as antioxidants: they are more efficient in converting Ce4+ into Ce3+ compared with the traditional ceria nanoparticles (Ceria NP), therefore a smaller dose suffice. After sepsis was induced in rats and mice with a puncture in the cecum (CLP), injection of 7CZ nanoparticles resulted in an increase in survival rate and a decrease in organ injuries.")
