German China
Shah’s team engineered living tumor cells using the gene editing tool Crispr-Cas9 and repurposed them to release tumor cell killing agent.  (Source: Pixabay)
Cell Therapy

Testing the Cancer Vaccine

Scientists at the Brigham and Women’s Hospital have tested a new cancer vaccine which kills as well as prevents brain cancer. The experts used a new cell therapy approach to eliminate established tumors and train the immune system to prevent cancer from recurring in the future.

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Providers on the topic

An IDH-mutant human glioma tumor, showing clusters of CD8+ T cells in green, and a gradient of purple to pink representing low to high D-2HG concentrations. CD8+ T cells were more abundant in areas with less D-2HG, and less abundant in regions with more D-2HG, suggesting that D-2HG has an effect on the immune cells. (Source: Gregory Baker, HMS)
Cancer Cells

How Certain Cancers Neutralize T Cells

New findings published by a team led by researchers at Harvard Medical School offer insight into how certain cancers disarm the immune system so that tumor cells can grow and divide. The findings highlight the role of the immune system in certain types of cancers, and could inform the development of better treatments.

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