Software Process Analyzer Software Optimizes Industrial Process Monitoring

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Thermo Fisher Scientific

KNF Neuberger GmbH

The Thermo Scientific Chromeleon 7 Process Analyzer software is Microsoft Windows 10 compatible and helps to streamline industrial process monitoring. The software facilitates continuous, reliable and compliant process monitoring using on-line ion chromatography and/or high performance liquid chromatography (HPLC) Process Analytical (PA) systems.

Now running on Microsoft Windows 10, the Thermo Scientific Chromeleon 7 Process Analyzer (Chromeleon 7 PA) software optimizes industrial process monitoring. When used with on-line ion chromatography (IC) and high-performance liquid chromatography (HPLC) PA systems, the software drives operational efficiencies and enables early, accurate detection of contaminants or irregularities that could impact product quality or system integrity. With reliable data acquisition, processing and reporting capabilities, the software facilitates well-informed, timely decision-making to prevent damage to facilities, reduce product failure and boost yield, shares the company.

The software enables simplified configuration, along with precise and integrated control over the entire sample and analytical process, allowing for unattended, 24/7 analyzer operation. As such, process analysts can focus on what matters most — interpreting and acting on the generated results, instead of monitoring their facility’s infrastructure. Users can benefit from a versatile interface and the additional functionality offered by the Thermo Scientific Chromeleon 7.3 chromatography data system (CDS) software, upon which it is based. Bidirectional communication with external data acquisition, automation and control systems is enabled using industry standard open platform communications (OPC). The software facilitates compliance with regulations like 21 CFR Part 11, a crucial requirement for United States Food and Drug Administration (US FDA) regulated industries, adds the firm.

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Reliable, accurate and timely process monitoring is of utmost importance across industrial operations to ensure variations are detected before they can impact yield or cause costly shutdowns. The software delivers unmatched process monitoring capabilities to allow customers to fine-tune their operations, maximize efficiency and reduce costs, opines the company.

The process monitoring capabilities of the software make it ideal for use across a number of industries, including pharmaceutical/biopharmaceutical production, chemical/petrochemical manufacturing, power, semiconductor manufacturing and water treatment. According to the firm, key applications include, but are not limited to:

• 1. Trace analysis of ultrapure water for use in semiconductor manufacturing and power plant cooling

• 2. Reaction and water purity monitoring, as well as cleaning validation, in pharmaceutical/biopharmaceutical production

• 3. Reaction process/endpoint determination and waste stream discharge monitoring in chemical/petrochemical manufacturing

• 4. Inflow and outflow monitoring in water treatment plants

• 5. Complete analyzer control – Comprehensive user management tools allow for controlled access and status monitoring of all analyzer components. Moreover, synchronized operation of multiple systems enables sequential sample analysis, maximizing throughput and productivity. Remote monitoring and control are also possible.

• 6. Automation – Programmable sample stream sequencing and analysis frequency, as well as automatic scheduling of system suitability samples, check standards and calibrations, facilitate simplified, unattended operation.

• 7. Safety – Real-time alerts when contaminants reach unacceptable levels, notifications of result-based events and hardware alarms drive appropriate, timely corrective actions. The software offers a broad range of preconfigured and user-defined conditional responses to keep the analyzers running and generating meaningful results.

• 8. Ease-of-use – A user-friendly interface allows for easy analyzer configuration, status control, operation monitoring and data reporting.

• 9. Information sharing – Seamless connectivity with external data acquisition, automation and control systems using the optional OPC.

• 10. Reporting flexibility – Reports with user- defined content.

• 11. Regulatory compliance – Support for 21 CFR Part 11 compliance, including secure, administrator-controlled user access and permissions, as well as maintenance of data integrity and audit trail logs showing date, time and actions being taken.

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