Cation Exchange Column Line Ion-Exchange Columns
Waters introduced a new cation exchange column line with specialized consumables to simplify and improve the characterization and monitoring of monoclonal antibody (mAb) therapeutics.
The new Bioresolve SCX mAb Columns and Vanguard FIT Cartridge technologies, together with a suite of complementary consumables, enable mAb charge-variant analyses as required by the World Health Organization, the U.S. Food and Drug Administration, and the International Conference on Harmonization for confirming the efficacy and safety of biologics and biosimilars within discovery, development, and manufacturing applications. Bioresolve SCX mAb Columns contain a strong-cation exchanger based on a novel polymeric composition, hydrophilic coating and multi-component surface chemistry. The base material consists of three-micron non-porous particles for optimal diffusion kinetics, high pressure capability and compatibility with HPLC, UHPLC and UPLC methods.