How to Collect Massive Quantities of Cell Culture Data

Micro Bioreactor System How to Collect Massive Quantities of Cell Culture Data

23.06.2017Editor: Jörg Kempf

The “ambr 15” automated micro bioreactor system from Sartorius Stedim Biotech (SSB) combined with a Nova Biomedical (Nova) “Bioprofile Flex2” automated cell culture analyzer enables rapid at-line sample collection and analysis of massive quantities of key cell culture data.

Related Company

Sartorius AG

Sartorius Stedim Biotech’s ambr 15 bioreactor system now can be combined with Nova’s Bioprofile Flex2 automated cell culture analyzer.
(Source: Sartorius)

SSB and Nova have collaborated to seamlessly integrate the software interface that controls the ambr 15 workstation for automated parallel processing of 24 or 48 single-use bioreactors (10–15 ml working volume) with the cell culture analysis capabilities of the Bioprofile Flex2. According to SSB, the combined system provides a unique tool to simultaneously run, sample and analyze a massive number of cell culture conditions during cell line and media development by Design of Experiments (DoE).

Combining the two systems enables fully integrated automatic sample transfer, analysis and automated feedback control in each single-use bioreactor. This allows collection of enormous quantities of cell culture data, including total and viable cell density, viability, cell diameter, pH, PCO2, PO2, glucose, lactate, glutamine, glutamate, ammonium, Na+, K+, Ca++ and osmolality, which can be sampled and measured with a complete cycle time of just 6–7 minutes.

The ambr 15 software simultaneously acquires the Bioprofile Flex2 data set and processes it, for example, by performing complex in-run calculations of how much feed volume to automatically add during a run. This saves time by significantly increasing the amount of consistent clone selection, media development and culture parameter data that a scientist can generate per run.

Unfold for details of your consent

Stand vom 23.03.2021

Naturally, we always handle your personal data responsibly. Any personal data we receive from you is processed in accordance with applicable data protection legislation. For detailed information please see our privacy policy.

Consent to the use of data for promotional purposes

I hereby consent to Vogel Communications Group GmbH & Co. KG, Max-Planckstr. 7-9, 97082 Würzburg including any affiliated companies according to §§ 15 et seq. AktG (hereafter: Vogel Communications Group) using my e-mail address to send editorial newsletters. A list of all affiliated companies can be found here

Newsletter content may include all products and services of any companies mentioned above, including for example specialist journals and books, events and fairs as well as event-related products and services, print and digital media offers and services such as additional (editorial) newsletters, raffles, lead campaigns, market research both online and offline, specialist webportals and e-learning offers. In case my personal telephone number has also been collected, it may be used for offers of aforementioned products, for services of the companies mentioned above, and market research purposes.

In case I access protected data on Internet portals of Vogel Communications Group including any affiliated companies according to §§ 15 et seq. AktG, I need to provide further data in order to register for the access to such content. In return for this free access to editorial content, my data may be used in accordance with this consent for the purposes stated here.

Right of revocation

I understand that I can revoke my consent at will. My revocation does not change the lawfulness of data processing that was conducted based on my consent leading up to my revocation. One option to declare my revocation is to use the contact form found at https://support.vogel.de. In case I no longer wish to receive certain newsletters, I have subscribed to, I can also click on the unsubscribe link included at the end of a newsletter. Further information regarding my right of revocation and the implementation of it as well as the consequences of my revocation can be found in the data protection declaration, section editorial newsletter.

(ID:44744304)

Micro Bioreactor System How to Collect Massive Quantities of Cell Culture Data

Subscribe to the newsletter now

Don't Miss out on Our Best Content

Consent to the use of data for promotional purposes