UHPLC system For analyzing protein-based pharmaceuticals
Shimadzu has introduced the new “Nexera Bio” solution, a biocompatible Ultra-High Performance Liquid Chromatography (UHPLC) system.
It offers the same reliability, robustness and expandability as other Nexera series UHPLC systems as Shimadzu states. It is suited for analyzing protein-based pharmaceuticals, antibody drugs and other substances developed or manufactured using biotechnologies. The Nexera Bio is compatible with mobile phase solvents containing high concentrations of salts or acids, and has also been designed to inhibit peak tailing caused by adsorption to tubing.
Furthermore Nexera Bio is equipped with product features such as maximum corrosion resistance, low surface activity and minimized sample loss. In the Nexera Bio system, crucial metal-free components define the wetted surfaces while maintaining a high-efficiency flow path (66 MPa). The system is unaffected by high salt content (KH2PO4 in H3PO4) or ion pairing agents (NH4PF6). It consists of stainless steel casing reinforced PEEK tubing (poly ether ether ketone), a high-performance engineered polymer with mechanical and chemical resistance properties.