Finding the Weak Spot in Bacteria to Fight Antibiotic Resistance
Surface representation of the MraY structure with inhibitor binding sites, or hot spots (HSs), color-coded and labelled as follows: uridine (red), uridine-adjacent (HS1; lime green), TM9b/LoopE (HS2; purple), caprolactam (HS3; pink), hydrophobic (HS4; cyan), Mg2 (HS5; gold), and tunicamycin (HS6; brown).
(Picture: Mashalidis EH. et al., Nature Communications, July 2, 2019)
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/cdn4.vogel.de/infinity/white.jpg "Surface representation of the MraY structure with inhibitor binding sites, or hot spots (HSs), color-coded and labelled as follows: uridine (red), uridine-adjacent (HS1; lime green), TM9b/LoopE (HS2; purple), caprolactam (HS3; pink), hydrophobic (HS4; cyan), Mg2 (HS5; gold), and tunicamycin (HS6; brown).")
