An international study has shown for the first time how empathetic correction of misinformation among vaccine-hesitant patients can significantly improve attitudes towards vaccination — and potentially boost vaccine uptake.
A study by the University of Bristol indicates that empathetic communication from healthcare professionals can significantly impact the attitudes of vaccine-hesitant individuals.
Research, led by the University of Bristol, also found this new style of communication could help build and maintain a positive relationship with health professionals, increasing trust and public confidence. With the UK currently facing a growing measles outbreak, fuelled by declining rates of the Measles, Mumps, and Rubella (MMR) vaccination, the results are timely and present important learnings for vaccine delivery programmes.
Its findings, published today in the journal Health Psychology, found the more than two-thirds (around 69 %) of vaccine-hesitant study participants who received empathetic engagement from a healthcare professional preferred this compared with a group who were just told the facts.
Lead author Dr Dawn Holford, Senior Research Associate in Psychology, said: “Although we expected people to generally respond more positively to an empathetic approach, it was surprising how much greater the preference for this style of communication was among those who expressed concerns about vaccination. The study highlights how the way misinformation is tackled, especially with vaccine averse groups, can play a vital role in changing perceptions which can be hard to shift.”
The study, which involved more than 2500 participants in the UK and US, compared their response to direct, factual communication with a novel dialogue-based technique empathising with their views, while also addressing false or misleading anti-vaccination arguments.
The results showed participants overall preferred the new approach, known as empathetic refutational interviewing – and this was response was strongest for the vaccine-hesitant, who found it more compelling than being presented purely with facts.
The majority of participants (around 64 %) who experienced the empathetic refutational interview also indicated they were more open to continuing the conversation with a healthcare professional, and around 12 % became more willing to be vaccinated compared to those participants who received the factual approach.
The interview technique comprises a four-step process. First the patient is invited to share their thoughts and concerns about vaccination so that healthcare professionals can understand their motivations and reservations. Then understanding and trust is built by affirming the patient's feelings and concerns. Thirdly, a tailored explanation is provided to challenge misconceptions, offering a truthful alternative to any misinformed beliefs. Finally, relevant facts about vaccination are provided, such as how they can benefit the individual by guarding against disease as well as collectively protecting others by reducing the spread and building vaccine-induced herd immunity.
Dr Holford said: “The findings actively demonstrate the power of communication, which healthcare professionals can use in their daily roles. Our study shows it is possible to gain trust and change minds if we take people’s concerns seriously and tailor our approach to help them make informed decisions about their health. This is hugely encouraging, especially with the growing influence of misinformation and fake news worldwide.”
The research is currently being developed into training tools and programmes to support healthcare professionals in the UK, France, Germany, and Romania.
During the Covid-19 pandemic, misinformation about vaccines fuelled vaccine hesitancy especially among vulnerable groups. In the wake of the pandemic, reduced uptake of various vaccines remains a major public health concern.
The UK Health Security Agency (UKHSA) recently declared a national incident due to a growing outbreak of measles, one of the most contagious viruses, with extra clinics and vaccine buses targeting communities with low vaccination rates. Uptake of the MMR (Measles, Mumps and Rubella) vaccine has fallen worldwide in the wake of the pandemic.
A recent study by the World Health Organisation found the global decline in childhood vaccinations, to protect against devastating but preventable diseases, was the largest sustained drop in around 30 years.
Co-author Stephan Lewandowsky, Chair in Cognitive Psychology at the University of Bristol, has led numerous studies demonstrating the alarming influence of misinformation and during the pandemic developed a unique online guide addressing and correcting the proliferation of misleading myths surrounding Covid-19 vaccines.
Date: 08.12.2025
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Professor Lewandowsky added: “It is important to understand the motivations underlying people’s vaccine hesitancy so we can correct misconceptions without confronting people’s deeply held attitudes head-on. By affirming and empathising with those deeply held attitudes we create a space where people are sufficiently comfortable to process corrective information, so they can make a better informed decision.”
Paper: ‘The Empathetic Refutational Interview to tackle vaccine misconceptions: four randomised experiments’ by Dawn Holford et al in Health Psychology