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USA: HRAM Technology Comprehensive Compound Characterization

| Editor: Alexander Stark

Thermo Fisher has updated their Orbitrap GC-MS systems with new capabilities in high resolution accurate mass (HRAM) GC-MS.

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The Q Exactive GC Orbitrap provides high-quality data for compound discovery, identification and quantitation giving users across metabolomics, food safety, environmental, pharma and toxicology applications high levels of accuracy in their data.
The Q Exactive GC Orbitrap provides high-quality data for compound discovery, identification and quantitation giving users across metabolomics, food safety, environmental, pharma and toxicology applications high levels of accuracy in their data.
(Source: Thermo Fisher)

Sunnyvale/USA — Enhancements include the addition of Variable electron Voltage (Vev) technology, the Orbitrap GC-MS HRAM Metabolomics Library and the Trace Finder Automated Compound Identification. These new capabilities are designed to provide highly sensitive, selective and accurate compound identification of complex samples for both research and routine laboratories performing gas chromatography mass spectrometry (GC-MS).

Users across metabolomics, food safety, environmental, pharma and toxicology applications are able to gain a deeper understanding of samples through the use of HRAM technology, the company claims.

The new capabilities included Vev technology that enables low electron voltage settings to be used during electron ionization (EI) protocols, promoting high mass signals and providing high sensitivity for compounds prone to extensive fragmentation.

The Orbitrap HRAM Metabolomics Library includes more than 800 metabolites and the spectra is refined and curated with the elemental composition of each EI fragment verified.

Furthermore, the new Trace Finder software features a specialized spectral deconvolution library and automated compound identification to enable identification of challenging compounds. With the addition of Kovats retention index to the scoring index of unknowns, user confidence in compound identification is improved, especially in relation to isomeric compounds.

The Q Exactive GC Orbitrap is a relatively easy-to-use GC-MS system that provides high quality data for compound discovery, identification and quantitation for comprehensive analyses. The Exactive GC Orbitrap GC delivers sensitive, routine grade performance in both targeted and non-targeted screening protocols.

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